Understanding the link between social contact patterns and influenza transmission

Friday, March 22, 2019

2.30 p.m.

ISI seminar room 1st floor

Jackie Kleynhans NICD - National Institute for Communicable Diseases, Johannesburg

The Prospective Household cohort study of Influenza, Respiratory Syncytial virus and other respiratory pathogens community burden and Transmission dynamics in South Africa (PHIRST) enrolled 327 households with 1684 individuals over a period of three years (2016-2018) from two sites within South Africa (rural and peri-urban) and followed each cohort over the course of one year by collecting nasopharyngeal swabs twice weekly to test for respiratory pathogens. The objectives of the study were to estimate the community burden and assess the transmission dynamics of influenza and respiratory syncytial virus. In 2018, the contact patterns of participants were investigated using wearable proximity sensors and contact diaries. We aim to describe contact patterns between household members and to estimate the association between contact patterns and transmission events of influenza virus. Preliminary results from the PHIRST study and the proposed analysis for the contact data will be presented.